徐洲更的头像

徐洲更

中国科学院分子植物科学卓越创新中心（CEMPS）博士后（王佳伟研究组）

浙江农林大学农学学士学位，中国科学院大学博士学位。主要研究方向为植物单细胞测序与跨物种细胞图谱构建。研究成果发表于 Cell、Science、Molecular Plant 等国内外重要学术期刊，相关成果入选 2024 年度"中国生命科学十大进展"。

入选"中国科学院特别研究助理资助项目"和"国家资助博士后研究人员计划（B档）"，具备优秀的学习能力和协作沟通能力，乐于探索并能够主动提出和解决问题。

基本信息

姓名：徐洲更

单位：中国科学院分子植物科学卓越创新中心

公众号：洲更的第二大脑

博客：xuzhougeng.top

教育经历

  • 2012-2016   浙江农林大学 — 农学学士学位
  • 2016-2023   中国科学院分子植物科学卓越创新中心 — 遗传学博士学位

工作经历

  • 2023 年 7 月至今 — 中国科学院分子植物科学卓越创新中心，博士后

专业技能

  • 基因组学的相关分析
  • 熟悉 Linux 和 Shell 编程，具备服务器管理能力
  • 熟悉 R 和 Python 编程语言，并了解数据结构和算法的应用
  • 基础的网站开发能力
  • 运用 AIGC 辅助项目开发

其他经历

自 2016 年读研以来，持续在网络上发表生物信息学相关教程，全网阅读量超过 200 万。在哔哩哔哩录制的生物信息学教学视频累计播放量约 10 万次，并通过邮件等方式帮助初学者答疑解惑。

发表论文

2025

  1. Shipeng Guo, Yanshuang Jiang, Jieya Zou, Mei Lu, Daxue Li, Qian Zhang, Weiwei Li, Lina Mao, Shengchun Liu, Zhougeng Xu, et al. GPSAdb 2.0: an expanded atlas of gene-perturbation transcriptomes with enhanced tools for regulatory gene discovery. Nucleic Acids Research, 2025. https://doi.org/10.1093/nar/gkaf1077
  2. Xiaofan Lu, Kailai Li, Zongcheng Li, Anqi Lin, Long Zhao, Rongfang Shen, Zhougeng Xu, Jianing Gao, et al. FigureYa: A Standardized Visualization Framework for Enhancing Biomedical Data Interpretation and Research Efficiency. iMetaMed. https://doi.org/10.1002/imm3.70005
  3. Hao-Chen Xue, Zhou-Geng Xu, Yu-Jie Liu, et al. A Unified Cell Atlas of Vascular Plants Reveals Cell-Type Foundational Genes and Accelerates Gene Discovery. Cell, 2025. https://doi.org/10.1016/j.cell.2025.07.036

2024

  1. Dong Zhai, Lu-Yi Zhang, Ling-Zi Li, Zhou-Geng Xu, et al. Reciprocal Conversion between Annual and Polycarpic Perennial Flowering Behavior in the Brassicaceae. Cell, 2024. https://doi.org/10.1016/j.cell.2024.04.047
  2. Chuan-Miao Zhou, Jian-Xu Li, Tian-Qi Zhang, Zhou-Geng Xu, et al. The Structure of B-ARR Reveals the Molecular Basis of Transcriptional Activation by Cytokinin. PNAS, 2024. https://doi.org/10.1073/pnas.2319335121
  3. Haibao Tang, Vivek Krishnakumar, Xiaofei Zeng, Zhougeng Xu, et al. JCVI: A Versatile Toolkit for Comparative Genomics Analysis. iMeta. https://doi.org/10.1002/imt2.211

2023

  1. L. Wang, M.-C. Wan, R.-Y. Liao, J. Xu, Z.-G. Xu, et al. The maturation and aging trajectory of Marchantia polymorpha at single-cell resolution. Developmental Cell, 2023.
  2. Hong-Bo Tang, Juan Wang, Long Wang, Guan-Dong Shang, Zhou-Geng Xu, et al. Anisotropic cell growth at the leaf base promotes age-related changes in leaf shape in Arabidopsis thaliana. The Plant Cell, 2023. https://doi.org/10.1093/plcell/koad031
  3. Ling-Zi Li, Zhou-Geng Xu, Tian-Guang Chang, et al. Common evolutionary trajectory of short life-cycle in Brassicaceae ruderal weeds. Nature Communications 14, 290 (2023). https://doi.org/10.1038/s41467-023-35966-7

2022

  1. Shipeng Guo, Zhougeng Xu, Xiangjun Dong, et al. GPSAdb: a comprehensive web resource for interactive exploration of genetic perturbation RNA-seq datasets. Nucleic Acids Research, 2022. https://doi.org/10.1093/nar/gkac1066
  2. Chen-Yi Li, Lei Yang, Yan Liu, Zhou-Geng Xu, et al. The Sage Genome Provides Insight into the Evolutionary Dynamics of Diterpene Biosynthesis Gene Cluster in Plants. Cell Reports, 2022. https://doi.org/10.1016/j.celrep.2022.111236
  3. Guan-Dong Shang, Zhou-Geng Xu, M.-C. Wan, et al. FindIT2: an R/Bioconductor package to identify influential transcription factor and targets based on multi-omics data. BMC Genomics 23, 272 (2022). https://doi.org/10.1186/s12864-022-08506-8
  4. Jian Gao, Ke Zhang, Ying-Juan Cheng, Sha Yu, Guan-Dong Shang, Fu-Xiang Wang, Lian-Yu Wu, Zhou-Geng Xu, et al. A Robust Mechanism for Resetting Juvenility during Each Generation in Arabidopsis. Nature Plants 8(3):257–268 (2022). https://doi.org/10.1038/s41477-022-01110-4
  5. L.-Y. Wu, G.-D. Shang, F.-X. Wang, J. Gao, M.-C. Wan, Z.-G. Xu, and J.-W. Wang. Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration. Developmental Cell, 2022.

2021

  1. Kun Huang, Xue-Xue Wu, Chen-Lu Fang, Z.-G. Xu, et al. Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA. Science, 2021. https://www.science.org/doi/10.1126/science.abj9184
  2. Yu-Jin Cheng, Guan-Dong Shang, Z.-G. Xu, et al. Cell division in the shoot apical meristem is a trigger for miR156 decline and vegetative phase transition in Arabidopsis. PNAS 118 (2021). https://doi.org/10.1073/pnas.2115667118
  3. Fu-Xiang Wang, Guan-Dong Shang, Lian-Yu Wu, Yan-Xia Mai, Jian Gao, Zhou-Geng Xu, Jia-Wei Wang. Protocol for assaying chromatin accessibility using ATAC-seq in plants. STAR Protocols 2(1):100289 (2021). https://doi.org/10.1016/j.xpro.2020.100289

2020

  1. Bin-Bin Ye, Guan-Dong Shang, Yu Pan, Zhou-Geng Xu, et al. AP2/ERF Transcription Factors Integrate Age and Wound Signals for Root Regeneration. The Plant Cell 32(1):226–241 (2020). https://doi.org/10.1105/tpc.19.00378
  2. Fu-Xiang Wang, Guan-Dong Shang, Lian-Yu Wu, Zhou-Geng Xu, et al. Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis. Developmental Cell 54(6):742–757.e8 (2020). https://doi.org/10.1016/j.devcel.2020.07.003

2019

  1. Tian-Qi Zhang, Zhou-Geng Xu, Guan-Dong Shang, Jia-Wei Wang. A Single-Cell RNA Sequencing Profiles the Developmental Landscape of Arabidopsis Root. Molecular Plant 12(5):648–660 (2019). https://doi.org/10.1016/j.molp.2019.04.004